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To create a new annotation for the active sequence press the Ctrl-N key sequence, select the New annotation toolbar button, or use the Add ‣ New annotation or New annotation context menu item:

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The dialog asks where to save the annotation. It could be either an existing annotation table object, a new annotation table, or an auto-annotations table (if it is available).

You can also specify the name of the group and the name of the annotation. If the group name is set to <auto> UGENE will use the group name as the name for the group. You can use the ‘/’ characters in this field as a group name separator to create subgroups. If the annotation name is set to by type UGENE will use the annotation type from the Annotation type: table as the name for the annotation. Also, you can add a description in the corresponding text field.

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