If the corresponding document is not locked, it is possible to edit a sequence.
To switch on the editing mode for the sequence, select the Edit sequence button on the left toolbar of the Details View:
<center> <br> <img src="/wiki/download/attachments/20880226/Editing Sequence.png"/> <br> </center>
A special cursor appears in this case, and the sequence can be edited as in a text editor:
One can also configure the way how annotations located in an edited region should be modified. To open a dialog with the settings select Edit–>Annotations settings on sequence editing in the Actions main menu or in the context menu of the Sequence View.
<center> <br> <img src="/wiki/download/attachments/20880226/Editing Sequence_1.png"/> <br> </center>
Select one of the following:
It is also possible to check the Recalculate values of qualifiers option in the dialog. If it is selected, qualifiers of all annotations are parsed on the sequence editing. Qualifiers values that specify coordinates (like "100..200") are re-calculated accordingly to the sequence modification. For example, the value might become "104..204", if four characters have been inserted before the corresponding annotation.
To replace a sequence with its reverse-complement sequence, select Edit–>Reverse-complement sequence in the Actions main menu or in the context menu of the Sequence View. The keyboard shortcut for this action is Ctrl + Shift + R / Cmd + Shift + R.
Use the Reverse sequence or Complement sequence items in the same menus to replace the sequence with its reverse or complement sequence.